ДИНАМИКА СТРУКТУРНО-ФУНКЦИОНАЛЬНЫХ СВОЙСТВ МЕМБРАН ЭРИТРОЦИТОВ У ДЕТЕЙ С ЦЕРЕБРАЛЬНОЙ ИШЕМИЕЙ ПОСЛЕ ЛЕЧЕНИЯ МЕТОДОМ ВОЙТА
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according to the method of V.B. Gavrilov et al. (1983, 1987). Antioxidant protection system was evaluated by the total antioxidant activity (AOA) of blood according to G. I. Klebanov et al. (1988), αtocopherol level according to the method of R. Ch. Cherniauskane et al. (1984), the superoxide dismutase (SOD) activity according to the method of H. P. Misra I., Fridovich (1972). The measurements were carried out using spectrofluophotometer «Shimadzu" RF-1501 and spectrophotometer "Shimadzu" RF-1650. Correlation analysis with the calculation of the Pearson correlation coefficient (r) for p <0.05 was carried out to evaluate the relationship. While working with patients and healthy children, ethical principles, recommended by the Declaration of Helsinki of the World Medical Association (2008), were followed. RESULTS Positive correlation between SOD and PI (r = 0.53) and negative correlation between DC and PI (r = -0.48), DC and RI (r = -0.48), reflecting the balance of physiological processes in a healthy body, were observed in the control group. The number of correlation relationships increases up to 6 in the group of children diagnosed with arterialhypertension. Correlations between SOD and PI (r = 0.54) do not differ from the data, received in the control group. The negative impact of lipid peroxidation products on the vascular wall demonstrates the correlation between MDA and TAMAX (r = - 0.59) and DC, and S/D (r = 0.56).Correlations between AOA and TAMAX (r = 0.59), α-tocopherol, and RI (r = -0.49) and AOA, and PI(r = 0.58) indicators prove the body's response to strengthening of the lipid peroxidation processes. Thus, the obtained data are consistent with the fact that LPO-AOP components affect changes of neurohumoral regulation of the blood vessels, playing an important role in the pathogenesis of arterial hypertension. REFERENCES 1. Grudyanov A.I. Ovchinnikova V.V. Inflammatory periodontal disease as a risk factor for diseases of the cardiovascular system // Dentistry. 2007. №5. S. 76 -78. 2. Kolesnikova LI, Dolgikh VV, Prokhorov Zh et al. Features of the system, consisting "of lipid peroxidation antioxidant protection" and calcium metabolism in adolescent children with essential arterial giperten Zee // Pediatrics. Journal of them. GN Speransky. 2010. T. 89. № 3. C. 10-14. 3. Kolesnikova LI, Dolgikh VV, Osipov EV et al. Oxidative stress in adolescents with labile hypertension // Siberian Medical Jour-nal (Tomsk). 2009. T. 24. № 3-1. S. 25-27. 4. Lebedenko I.Yu., Khetagurov S.K. Functional state of dental system in patients with essential hypertension // Russian Journal of Dentistry. 2006. № 3. P. 4-8. DOI:10.12737/12380 ДИНАМИКА СТРУКТУРНО-ФУНКЦИОНАЛЬНЫХ СВОЙСТВ МЕМБРАН ЭРИТРОЦИТОВ У ДЕТЕЙ С ЦЕРЕБРАЛЬНОЙ ИШЕМИЕЙ ПОСЛЕ ЛЕЧЕНИЯ МЕТОДОМ ВОЙТА